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How long does it take weight loss drugs to work?

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May 31, 2025
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How long does it take weight loss drugs to work?
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Weight loss medications like Ozempic and Wegovy have become increasingly popular over the past few years.

For those who are looking into using a weight loss drug, how fast they work often comes into question. While the timeline for noticeable changes varies from person to person, people have often noticed changes in their appetite and weight within the first few weeks of use.

According to the Mayo Clinic, most weight loss occurs within the first four to five months of use. Long-term use of weight loss drugs can lead to sustained weight decreases and improvements in overall metabolic health but must be paired with healthy eating and exercise.

There are a few factors that can contribute to how quickly weight loss drugs can work for each individual, like metabolism and following the treatment plan.

People with a higher metabolism are more likely to see results faster from weight loss drugs compared to those with a lower metabolic rate.

Lifestyle factors like dietary habits, exercise routines, adequate sleep and stress management also play a role in the speed at which weight loss drugs work. Since the drugs can suppress your appetite, it can be challenging to get proper nutrition and possibly lead to side effects.

Doctors say to manage any side effects, you should follow a nutritionally balanced diet and drink enough fluids.

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